Carbamazapine causes severe side effects in users. One of these is Stevens-Johnson Syndrome (a form of Toxic Epidermal Necrolysis [TEN]), a horrific skin condition in which cell death causes the outer layer of skin cells (the epidermis) to separate from the inner layer (dermis). Although it first appears as an upper respiratory tract infection, patients? skin turns red, fills with fluid, and then peels off. The disease has a high mortality rate; 30-40 percent of victims die due to bacterial or fungal infections.
Suicidal Ideations and Behaviors
Like many other epileptic drugs, Carbamazapine causes suicidal ideations in users. The FDA began investigating this phenomenon in 2005, and in 2008 it completed a study of 28,000 people on antiepileptics compared to 16,000 people given placebos. About 0.43 percent of those on the antiepileptics experienced suicidal ideations as opposed to 0.22 percent of those on the placebos. Most of these began within the first week of use and continued for
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